S2303 |
This study is for patients who have progressed on standard of care treatment for gastric or esophageal cancer. The study looks at adding Nivolumab to 2nd line treatment to see if it improves outcomes. |
Cancer |
Gastric or Esophageal |
Basic |
The purpose of this study is to test if different mobile or wearable devices can measure how much time a person's heart is in atrial fibrillation over a period of 4 months. |
Heart & Vascular |
Atrial Fibrillation |
Picasso |
The study is trying to assess the safety and efficacy of fixing the narrowing in your carotid artery using a stent versus using a balloon or suction method when performed at the same time as the mechanical thrombectomy. |
Neurosciences |
Stroke |
EA5221 |
The purpose of this study is to determine in the older adult population if immunotherapy alone is better than immunotherapy + chemotherapy. Patients must be 70+ with diagnosis of Non-Small Cell Lung Cancer. |
Cancer |
Non-Small Cell Lung Cancer |
NRG BN011 |
The purpose of this study is to determined if combination therapy radiation is more effective than single agent therapy with radiation. Patients must be diagnosed with a Methylated MGMT promoter Gliblastoma. |
Cancer |
Gliblastoma |
NRG CC011 |
This study is for patients with stage 1-3 breast cancer. Patient must be > 6 months to 5 years out from treatment and experiencing symptoms of brain fog. The study using cognitive training to try to improve brain fog symptoms. |
Cancer |
Breast |
S2010 |
This study is for patients with stage 1-3 hormone positive breast cancer that plan to receive endocrine therapy. The study using cognitive training to try to keep patients on endocrine therapy despite the side effects of therapy. |
Cancer |
Breast |
COMPaCT |
This study is for patients who have a diagnosis and medical condition that requires a cholecystectomy. A cholecystectomy is the surgical removal of the gallbladder, which stores bile for use in digestion. The purpose of this study is to collect information about the outcome of the surgery, as well as the patient’s pain and quality of life after laparoscopic or robotic-assisted cholecystectomy, in order to provide more information to the surgical community. |
Gastroenterology |
Surgery |
Librexia ACS |
The purpose of this study is to see if an experimental drug, called milvexian is safe, effective and useful in reducing risk of developing blood clots, stroke, or another heart attack among subjects with a recent heart attack or angina (chest pain) episode. An experimental drug is one that is not approved by the United States Food and Drug Administration (FDA). |
Heart & Vascular |
Atrial Fibrillation |
A032103 |
The purpose of this study is to use central DNA testing to monitor recurrance in patients with urothelial cancer. You must have had a radical cysectomy and lymph node dissection with no evidence of residual cancer. |
Cancer |
Urothelial |
EA8211 |
This study is for patients with renal cell cancer who have a total of 2-5 metastatic lesions. The study is looking at using radiation to the metastatic sites in combination with chemotherapy. |
Cancer |
Metastatic Renal Cell |
EAY191-N5 |
This study is for patient's who have HER2+ gynecologic cancers or other solid tumors. Cannot have breast cancer. You must have recurrent disease or progressed on treatment. |
Cancer |
Her2+ Solid Tumors |
S2101 |
This study is for patients with Stage III or IV, unresectable, recurrent, or metastatic melanoma. This study uses Nivolumab and Cabozantinib to treat patients. |
Cancer |
Melanoma |
Tandem |
The purpose of this study is to compare the effects of the study drug, obicetrapib when administered together with the drug ezetimibe as a fixed dose combination. A fixed dose combination means the two drugs are combined into a single tablet. The study will also check how safe obicetrapib and ezetimibe is for participants with high levels of LDL-C in the blood. |
Heart & Vascular |
Lipid Management; Cardiovascular Disease |
SOUL Music |
This is a multicenter prospective trial with randomized and observational cohorts assessing patient-reported outcomes and unplanned healthcare utilization following ureteroscopic treatment of renal and ureteral stones, with placement versus omission of a ureteral stent. Eligible participants in the randomization trial will be randomized to ureteroscopy with stent placement or stent omission. Eligible participants that consent to the observational only cohort will complete surveys and the treating physicians will decide the treatment options for the participants. |
Surgery |
Urinary Stone Disease |
EAY191-E5 |
This study is for patients who have a KRAS G12C mutation and advanced/metastatic solid tumors. Your cancer must have progressed on standard of care therapy. You cannot have colorectal cancer or non-small cell lung cancer. |
Cancer |
Solid Tumors |
S2013 |
The purpose of this study is the look at the side effects of immunotherapy treatment. You must be starting immunotherapy alone not in combination with other treatments. You must have a solid tumor. |
Cancer |
Solid Tumors |
Intuitive Surgical Ureter |
The purpose of this study is to investigate whether the study drug may allow the surgeon to better see the ureters when using the da Vinci Surgical System for gynecological surgery. |
Surgery |
Gynecology |
NRG-BR009 |
The purpose of this study is treat breast cancer after surgery. You must have estrogen positive breast cancer and an oncotype score ≤25. This study looks at adding chemotherapy to the standard treatment of ovarian function suppression and aromatase inhibitor. |
Cancer |
Breast |
GU012 |
The purpose of this study is to compare standard immunotherapy with immunotherapy and radiation. You must be diagnosed with metastatic renal cell cancer and have not had surgery for this cancer. |
Cancer |
Metastatic Renal Cell |
S2209 |
This study is for frail-intermediately fit newly diagnosed multiple myeloma patients. Your current lab values will be used to determine if you qualify for this study. This study compares different chemo regimens to determine the effectiveness of them. |
Cancer |
Multiple Myeloma |
A031701 |
The purpose of this study is to compare standard or dose dense gemcitabine and cisplatin chemo. You must have been diagnosed with muscle invasive bladder cancer. |
Cancer |
Bladder |
A031702 |
The purpose of this study is to look at the effectineness of cabozantinib combined with nivolumab and ipilimubmab. You must be diagnosed with a rare genitourinary tumor of the kidney, bladder, ureters or penis. |
Cancer |
Rare Genitourinary |
A031902 |
The purpose of this study is to evaluate progression free survival and overall survival with the use of enzalutamide and rucaparib vs enzalutamide alone. You must be diagnosed with metastatic castration-resistant prostate cancer. This must be your first treatment for your metastatic cancer. |
Cancer |
Metastatic Prostate |
A081801 (sub study A151216) |
The purpose of this study is to compare disease free survival when adding immunotherapy to initial chemotherapy vs immunotherapy only in maintenance therapy. You must be diagnosed with stage 2 or stage 3 non-small cell lung cancer (NSCLC). |
Cancer |
Non-Small Cell Lung |
A082002 |
The purpose of this study is to determine in SBRT (stereotactic body radiation therapy) improves survival in advanced stage NSCLC. You must be diagnosed with stage 3 or 4 Non-Small Cell Lung Cancer (NSCLC). |
Cancer |
Non-Small Cell Lung |
A212102 |
This is a study looking at determining effectiveness of a multicancer early dectection blood test. Participants are healthy subjects, those with a known cancer diagnosis, and those with high suspicion of cancer. |
Cancer |
All tumor types |
EA2183 |
The purpose of this study is to determine if adding radiation to chemo is beneficial. You must be diagnosed with metastatic HER2 negative esophageal and gastric cancer. |
Cancer |
Esophageal |
EA5182 |
This study is comparing Osimertinib and Bevacizumab vs Osimertinib alone as first-line treatment for patients with metastatic EGFR mutant Non-Small Cell Lung Cancer (NSCLC). You must be diagnosed with stage 3 or 4 NSCLC. |
Cancer |
Non-Small Cell Lung |
EAA173 |
The purpose of this study is determine if dararumumab enhances the effectiveness of revlimid in patients with smoldering myeloma. You must be diagnosed with asymptomatic high risk smoldering multiple myeloma. |
Cancer |
Smoldering Myeloma |