Search for Current Clinical Trials

Study Name Description Trial Category Trial SubCategory
Aveir DR The objective for this study is to confirm the safety and effectiveness of the Aveir LP (Leadless Pacemaker) System in a subject population indicated for a dual chamber pacemaker. Heart & Vascular Cardiac Arrhythmia
Complete TAVR The purpose of this study is to determine whether restoring blood flow to all blocked or narrowed arteries via percutaneous coronary intervention (PCI) using coronary stents is better than treating the coronary artery disease (CAD) with medications in patients with CAD who had successful transcatheter aortic value replacement (TAVR) with a balloon expandable heart valve. The study will also compare measurements of hemodynamics (blood flow and blood pressure) that are taken during on-table procedures (TAVR and PCI) with those taken by echocardiography (heart ultrasound). Heart & Vascular Cardiovascular Disease
Iocyte Faraday STEMI drug The purpose of this study is to evaluate the efficacy and safety of the study drug vs placebo in subjects with an anterior ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). Heart & Vascular Heart Failure
Node X Participants must have participated in a prior study with the investigational drug etripamil (the NODE-301, NODE-302, or NODE-303 study). The study is being done to determine the safety of etripamil 70 mg for the treatment of multiple episodes of PSVT in an at-home setting. Heart & Vascular Cardiac Arrhythmia
PPP/PAN/PSR This study is a registry study. The purpose is to collect information over time about how Medtronic products are working and/or the outcome of the treatment. The registry will be used to support post-market surveillance activities and post-approval studies (e.g., to collect safety and performance information). In addition, it will be used to obtain clinical evidence for the development and improvement of medical devices, therapies, device guidelines, patient services/solutions and provide clinical data to support health economics and clinical outcomes research. The registry is not an experimental clinical study. Heart & Vascular Cardiac Arrhythmia
Rethink Reflux Registry The purpose of this study is to gather information about how the LINX device works over an extended period in people with GERD (gastric esophageal reflux disease). Surgery GERD (Gastro Esophageal Reflux Disease)
Arrhythmia Detection After Myocardial Infarction (AID-MI) This study will evaluate the use of an insertable cardiac monitor in patients following an acute myocardial infarction (heart attack) to determine if cardiac monitoring results in more rhythm-related findings that change management compared to standard of care post heart attack management in patients who do not receive the insertable cardiac monitor. Heart & Vascular Cardiac Arrhythmia
CREST 2 LOE Long-Term Observational Extension of Participants in the CREST-2 Randomized Clinical Trial (C2LOE) Heart & Vascular Carotid Stenosis
Real AF Real-world Experience of Catheter Ablation for the Treatment of Symptomatic Paroxysmal and Persistent Atrial Fibrillation Using Novel Contact Force Technologies: REAL AF Registry Heart & Vascular Atrial Fibrillation
V-Inception A randomized, controlled, multicenter, open-label trial comparing a hospital post-discharge care pathway involving aggressive LDL-C management that includes inclisiran with usual care versus usual care alone in patients with a recent acute coronary syndrome (VICTORION-INCEPTION) Heart & Vascular Lipid Management
EA2176 The purpose of this study is to see if adding immunotherpy to chemo is more effective than chemo alone. You must be diagnosed with metastatic anal cancer. Cancer Metastic Anal
S1925 The purpose of this study is to compare early intervention with Venetoclax and Obinutuzumab vs delayed therapy in newly diagnosed asymptomatic high0risk patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL). You must have been diagnosed with CLL or SLL within the last 12 months. Cancer Hematology
A031803 The purpose of this study is to determine the effectiveness of intravesical gemcitabine in combination with prembrolizumab. Patients must have been diagnosed with invasive bladder and already received chemo. Cancer Bladder
AALL08B1 Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) Childhood Cancers Leukemia
AALL0932 Treatment of Patients with Newly Diagnosed Standard Risk B-Precursor Acute Lymphoblastic Leukemia (ALL) Childhood Cancers Leukemia
AALL1231 A Phase lll Randomized Trial Investigating Bortezomib (NSC#681239; IND# 58443) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T-Lymphoblastic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LLy) Childhood Cancers Leukemia
AALL1521 A Phase 2 study of the JAK1/JAK2 Inhibitor Ruxolitinib with Chemotherapy in Children with De Novo High-Risk CRLF2 Rearranged and/ or JAK Pathway-Mutant Acute Lymphoblastic Leukemia Childhood Cancers Leukemia
Acoustic Diagnosis of Gastroesophageal Reflux Disease Baby/Child Reflux Disease
ANBL1232 Utilizing Response-and Biology-Based Risk Factors to Guide Therapy in Patients with Non-High Risk Neuroblastoma Childhood Cancers Blastoma
APEC14B1 EveryChild A Registry, Eligibility Screening, Biology and Outcome Study Childhood Cancers Registry
Bayer ON-TRK The purpose of this study is to learn about the effectiveness of Vitrakvi in patients with TRK Fusion cancer. You must have a advanced solid tumor with a NTRK gene fusion. Cancer All tumor types
Champion AF The primary objective of this study is to determine if left atrial appendage closure with the WATCHMAN FLX device is a reasonable alternative to non-vitamin K oral anticoagulants in patients with non-valvular atrial fibrillation. Heart & Vascular Atrial Fibrillation
COG-AALL05B1 Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens Childhood Cancers Leukemia
COG-AALL1331 Risk Stratified Randomized Phase lll Testing of blinatumomab (IND#117467, NCS#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL) Childhood Cancers Leukemia
COG-ACNS0332 Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other than Average Risk Medulloblastoma/PNET Patients Childhood Cancers Blastoma
COG-ACNS0831 Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 years Childhood Cancers Glioma
COG-AEWS07B1 A Children's Oncology Group Protocol for Collecting and Banking Ewing Sarcoma Specimens Childhood Cancers Sarcoma
COG-AHEP0731 Treatment of Children with All Stages of Hepatoblastoma Childhood Cancers Blastoma
COG-AHOD1331 A randomized Phase III Study of Brentuximab Vedotin (SGN-35, IND # 117117) for Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents Childhood Cancers Lymphoma
COG-ANBL00B1 Neuroblastoma Biology Studies Childhood Cancers Blastoma